distribution of hepatitis b virus (hbv) genotypes among hbv carriers in isparta

نویسندگان

süleyman onal

selcuk kaya buket cicioglu aridogan

emel sesli cetin emel sesli cetin

buket cicioglu aridogan selcuk kaya

süleyman onal

چکیده

the aim of this study was to investigate the prevalence of hepatitis b virus (hbv) genotypes in isparta, southwest of turkey, as well as the clinical features and transmission route for patients with hbv infections. methods: patients (n = 135) with hbv infection were included in the study. epidemiological and clinical data were obtained. hbv genotypes were determined with a pres2 epitope elisa kit. results: although the hbv transmission route remained unidentified in 51.1% of the patients, blood contact was determined as the most common probable transmission route (38.5%). one hundred twenty-four (91.8%) of 135 samples, could be genotyped. one hundred fifteen (85.1%) were genotyped as type d/e, six (4.4%) were genotyped as type a, two (1.4%) were genotyped as type c, and one (0.7%) were genotyped as type f. conclusion: genotype d/e is determined as the predominant hbv genotype circulating in isparta, southwest of turkey. no relationship between genotypes and disease severity and transmission route has been detected.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Distribution of Hepatitis B Virus (HBV) Genotypes among HBV Carriers in Isparta

The aim of this study was to investigate the prevalence of hepatitis B virus (HBV) genotypes in Isparta, Southwest of Turkey, as well as the clinical features and transmission route for patients with HBV infections. Methods: Patients (n = 135) with HBV infection were included in the study. Epidemiological and clinical data were obtained. HBV genotypes were determined with a preS2 epitope ELISA ...

متن کامل

Distribution of hepatitis B virus (HBV) genotypes among HBV carriers in Isparta.

BACKGROUND The aim of this study was to investigate the prevalence of hepatitis B virus (HBV) genotypes in Isparta, Southwest of Turkey, as well as the clinical features and transmission route for patients with HBV infections. METHODS Patients (n = 135) with HBV infection were included in the study. Epidemiological and clinical data were obtained. HBV genotypes were determined with a preS2 ep...

متن کامل

Determination of Hepatitis Delta Virus Genotype among HBV Carriers in Southwest of Iran

Background and Aims: HDV is a defective satellite virus and classified in genus Deltavirus. Its disease is related and limited to HBV-infected patients. Acute infection of delta agent occurs in two different patterns simultaneous infection with both HBV & HDV or super infection of chronically HBV infected patients that lead to more sever type of hepatitis. According to genetic diversity of geno...

متن کامل

Steroid-free chemotherapy decreases risk of hepatitis B virus (HBV) reactivation in HBV-carriers with lymphoma.

Reactivation of hepatitis is one of the most serious complications of chemotherapy in lymphoma patients who are carriers of the hepatitis B virus (HBV). Glucocorticoids are linked to increased risk of HBV reactivation. This study seeks to clarify whether removal of glucocorticoids from chemotherapy regimens may decrease the risk of HBV reactivation. Eligible patients were seropositive for hepat...

متن کامل

Doxorubicin activates hepatitis B virus (HBV) replication in HBV-harboring hepatoblastoma cells. A possible novel mechanism of HBV reactivation in HBV carriers receiving systemic chemotherapy.

BACKGROUND Reactivation of HBV replication is a clinically significant complication in HBV(+) patients receiving chemotherapy. We recently found that nearly half of the HBV reactivation in lymphoma patients occurred within 2 weeks of the first dose of chemotherapy. We hypothesized that mechanisms other than immunosuppression, such as direct stimulation of HBV replication by anticancer drugs, mi...

متن کامل

Lack of implementation of Hepatitis B Virus (HBV) vaccination policy in household contacts of HBV carriers in Italy

BACKGROUND In Italy, HBV vaccination is recommended and offered free of charge through the National Health Service to selected population groups -- e.g., family members of an HBsAg carrier, healthcare workers, newborns and those who were 12-years old in 1991. However, a significant proportion of cases of acute hepatitis B still occur in Italy among persons who should have been vaccinated. We an...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian biomedical journal

جلد ۱۱، شماره ۱، صفحات ۵۹-۶۳

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023